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We know more about the movement of celestial bodies than about the soil underfoot.

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Art is the queen of all sciences communicating knowledge to all the generations of the world.

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I believe there exists, & I feel within me, an instinct for the truth, or knowledge or discovery, of something of the same nature as the instinct of virtue, & that our having such an instinct is reason enough for scientific researches without any practical results ever ensuing from them.

Nor am I less persuaded, that you will agree with me in opinion, that there is nothing, which can better deserve your patronage, than the promotion of Science and Literature. Knowledge is in every Country the surest basis of public happiness. In one, in which the measures of Government receive their impression so immediately from the sense of the Community as in ours, it is proportionally essential.

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To explain all nature is too difficult a task for any one man or even for any one age. 'Tis much better to do a little with certainty, and leave the rest for others that come after you, than to explain all things by conjecture without making sure of anything.