We are to admit no more causes of natural things than such as are both true and sufficient to explain their appearances.

We are certainly not to relinquish the evidence of experiments for the sake of dreams and vain fictions of our own devising; nor are we to recede from the analogy of Nature, which is wont to be simple and always consonant to itself.

This principle of nature being very remote from the conceptions of Philosophers, I forbore to describe it in that book, least I should be accounted an extravagant freak and so prejudice my Readers against all those things which were the main designe of the book.

Those who are inspired by a model other than Nature, labor in vain.

I believe there exists, & I feel within me, an instinct for the truth, or knowledge or discovery, of something of the same nature as the instinct of virtue, & that our having such an instinct is reason enough for scientific researches without any practical results ever ensuing from them.

He who is not content to look, like a savage, at the phenomena of nature as disconnected, cannot any longer believe that man is the work of a separate act of creation ... Man is the co-descendant with other mammals of a common progenitor.