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I believe there exists, & I feel within me, an instinct for the truth, or knowledge or discovery, of something of the same nature as the instinct of virtue, & that our having such an instinct is reason enough for scientific researches without any practical results ever ensuing from them.

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We are not here concerned with hopes or fears, only with truth as far as our reason permits us to discover it.

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Every serious scientific worker is painfully conscious ... of being relegated to an ever-narrowing sphere of knowledge.

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Nor am I less persuaded, that you will agree with me in opinion, that there is nothing, which can better deserve your patronage, than the promotion of Science and Literature. Knowledge is in every Country the surest basis of public happiness. In one, in which the measures of Government receive their impression so immediately from the sense of the Community as in ours, it is proportionally essential.