I believe there exists, & I feel within me, an instinct for the truth, or knowledge or discovery, of something of the same nature as the instinct of virtue, & that our having such an instinct is reason enough for scientific researches without any practical results ever ensuing from them.

To explain all nature is too difficult a task for any one man or even for any one age. 'Tis much better to do a little with certainty, and leave the rest for others that come after you, than to explain all things by conjecture without making sure of anything.

Art is the queen of all sciences communicating knowledge to all the generations of the world.

I do not know what I may appear to the world, but to myself I seem to have been only like a boy playing on the seashore, and diverting myself in now and then finding a smoother pebble or a prettier shell than ordinary, whilst the great ocean of truth lay all undiscovered before me.

Nor am I less persuaded, that you will agree with me in opinion, that there is nothing, which can better deserve your patronage, than the promotion of Science and Literature. Knowledge is in every Country the surest basis of public happiness. In one, in which the measures of Government receive their impression so immediately from the sense of the Community as in ours, it is proportionally essential.

There is nothing which can better deserve your patronage, than the promotion of science and literature. Knowledge is in every country the surest basis of public happiness.